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产品目录

TIM3/HAVCR2抗体图片
产品货号:
Z38397
中文名称:
TIM3/HAVCR2抗体
英文名称:
Anti-TIM3/HAVCR2 Antibody (Clone#10C10)
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-TIM3/HAVCR2 Antibody (Clone#10C10)
指标别名CD366;HAVcr 2;HAVCR2;KIM 3;T cell membrane protein 3;Tim 3;TIM3;TIM-3;TIMD 3;TIMD3
克隆性Monoclonal
检验物种human
应用范围ELISA,WB,IHC,ICC,IF,FCM
基因名称HAVCR2
克隆号10C10
抗体来源Mouse
免疫原TIM-3 antibody was raised against the extracellular domain of human TIM-3
计算分子量33kDa
成分TIM-3 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.
纯化方式TIM-3 Antibody is supplied as protein A purified IgG1.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料The immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-污producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells.It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses,and is also highly expressed on regulatory T cells,monocytes,macrophages,and dendritic cells (1).TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice;blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).
Uniprot IDQ8TDQ0
基因名全称Hepatitis A virus cellular receptor 2
蛋白名全称Hepatitis A virus cellular receptor 2
推荐稀释比TIM-3 antibody can be used for ELISA starting at 0.1μg/mL.For Western blot start at 1μg/mL.For Immunocytochemistry start at 1μg/mL.For Immunofluorescence start at 10μg/mL.For Immunohistochemistry start at 5μg/mL.For Flow Cytometry start at 0.1μg/mL.

相关搜索:TIM3/HAVCR2抗体TIM3抗体HAVCR2单抗Anti-TIM3/HAVCR2 Antibody (Clone#10C10)
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