产品货号:
Z38397
中文名称:
TIM3/HAVCR2抗体
英文名称:
Anti-TIM3/HAVCR2 Antibody (Clone#10C10)
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TIM3/HAVCR2 Antibody (Clone#10C10) |
指标别名 | CD366;HAVcr 2;HAVCR2;KIM 3;T cell membrane protein 3;Tim 3;TIM3;TIM-3;TIMD 3;TIMD3 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,ICC,IF,FCM |
基因名称 | HAVCR2 |
克隆号 | 10C10 |
抗体来源 | Mouse |
免疫原 | TIM-3 antibody was raised against the extracellular domain of human TIM-3 |
计算分子量 | 33kDa |
成分 | TIM-3 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol. |
纯化方式 | TIM-3 Antibody is supplied as protein A purified IgG1. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-污producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells.It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses,and is also highly expressed on regulatory T cells,monocytes,macrophages,and dendritic cells (1).TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice;blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3). |
Uniprot ID | Q8TDQ0 |
基因名全称 | Hepatitis A virus cellular receptor 2 |
蛋白名全称 | Hepatitis A virus cellular receptor 2 |
推荐稀释比 | TIM-3 antibody can be used for ELISA starting at 0.1μg/mL.For Western blot start at 1μg/mL.For Immunocytochemistry start at 1μg/mL.For Immunofluorescence start at 10μg/mL.For Immunohistochemistry start at 5μg/mL.For Flow Cytometry start at 0.1μg/mL. |
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